Amino acid reabsorption in the proximal tubule of rat kidney: Stereospecificity and passive diffusion studied by continuous microperfusion

@article{Silbernagl1977AminoAR,
  title={Amino acid reabsorption in the proximal tubule of rat kidney: Stereospecificity and passive diffusion studied by continuous microperfusion},
  author={Stefan Silbernagl and Harald V{\"o}lkl and Gertraud Vetter},
  journal={Pfl{\"u}gers Archiv},
  year={1977},
  volume={367},
  pages={221-227}
}
Renal tubular reabsorption of glycine and of thel- andd-isomers of histidine, serine, phenylalamine, methionine, proline and cystine was investigated in vivo et situ by continuous microperfusion of single proximal convolutions of the rat kidney. In the case of glycine and thel-isomers, tubular reabsorption is saturable to a great extent. Thed-amino acids are reabsorbed much more slowly than the respectivel-forms. Furthermore in the case of methionine and perhaps also of proline, serine and… CONTINUE READING
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