Amino acid neurotransmitter release in the preoptic area of rats during the positive feedback actions of estradiol on LH release.

@article{Jarry1992AminoAN,
  title={Amino acid neurotransmitter release in the preoptic area of rats during the positive feedback actions of estradiol on LH release.},
  author={Hubertus Jarry and B. Hirsch and Sabine Leonhardt and Wolfgang Wuttke},
  journal={Neuroendocrinology},
  year={1992},
  volume={56 2},
  pages={
          133-40
        }
}
To investigate the role of amino acid neurotransmitters in the regulation of LH secretion in ovariectomized (ovx) rats with or without estrogen substitution, we measured the release rates of gamma-aminobutyric acid (GABA), taurine, glycine, aspartate, glutamate, homocysteic acid, and also of the neurally inactive amino acids serine and glutamine in push-pull perfusate samples of the preoptic/anterior hypothalamic area (PO/AH) collected at 30-min intervals. To achieve this we had to develop a… CONTINUE READING

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