Amino acid composition and sequence of dermorphin, a novel opiate-like peptide from the skin of Phyllomedusa sauvagei.

@article{Montecucchi1981AminoAC,
  title={Amino acid composition and sequence of dermorphin, a novel opiate-like peptide from the skin of Phyllomedusa sauvagei.},
  author={Piercarlo Montecucchi and Roberto de Castiglione and S Piani and L. Gozzini and Vittorio Erspamer},
  journal={International journal of peptide and protein research},
  year={1981},
  volume={17 3},
  pages={275-83}
}
Dermorphin, a heptapeptide with very potent opiate-like activity, has been isolated from methanol extracts of the skin of the South American frog Phyllomedusa sauvagei. The amino acid sequence of the peptide is: H-Try-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2. Dermorphin presents striking differences from the known enkephalins; it offers a surprising example of a peptide from Vertebrata containing a D-amino acid residue in its sequence.