Amino acid and protein oxidation in cardiovascular disease

  title={Amino acid and protein oxidation in cardiovascular disease},
  author={M. C. Brennan and Stanley L. Hazen},
  journal={Amino Acids},
 Substantial evidence suggests that oxidative events contribute to the pathogenesis of atherosclerotic heart disease. For example, animal model data and numerous in vitro studies point to specific pathways as participants in disease initiation and progression. Moreover, recent clinical studies demonstrate clinical utility in monitoring systemic levels of protein-bound nitrotyrosine as a predictor of risk for coronary artery disease, atherosclerotic burden, and response to statin therapy… CONTINUE READING


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