Aminated gelatin microspheres as a nasal delivery system for peptide drugs: evaluation of in vitro release and in vivo insulin absorption in rats.

Abstract

Aminated gelatin microspheres (AGMS) was investigated as a nasal drug delivery system for peptide drugs. The in vitro drug release from microspheres was evaluated using a fluorescein-labeled insulin (RITC-insulin) and FITC-dextran with a molecular weight of 4.4 kDa (FD-4) as model drugs. RITC-insulin release from AGMS was significantly slower than from… (More)

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Cite this paper

@article{Wang2006AminatedGM, title={Aminated gelatin microspheres as a nasal delivery system for peptide drugs: evaluation of in vitro release and in vivo insulin absorption in rats.}, author={Jian Wang and Yasuhiko Tabata and Kazuhiro Morimoto}, journal={Journal of controlled release : official journal of the Controlled Release Society}, year={2006}, volume={113 1}, pages={31-7} }