Amidine surface modification of poly(acrylonitrile-co-vinyl chloride) reduces platelet adhesion.

Abstract

The surface nitrile groups of solvent-cast polyacrylonitrile-co-vinyl chloride (PAN-VC) films were converted into amidine groups through a two-step process analogous to Pinner's method of 1877. The amidine groups were hypothesized to reduce platelet adhesion and activation through the inhibition of the classical complement pathway, as was noted for… (More)
DOI: 10.1002/jbm.a.32022

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