Amide proton transfer MR imaging of prostate cancer: a preliminary study.

  title={Amide proton transfer MR imaging of prostate cancer: a preliminary study.},
  author={Guang Jia and Ronney Abaza and Joanna D Williams and Debra L. Zynger and Jinyuan Zhou and Zarine K. Shah and Mitva Patel and Steffen Sammet and Lai Wei and Robert R. Bahnson and Michael V. Knopp},
  journal={Journal of magnetic resonance imaging : JMRI},
  volume={33 3},
PURPOSE To evaluate the capability of amide proton transfer (APT) MR imaging for detection of prostate cancer that typically shows a higher tumor cell proliferation rate and cellular density leading to an MRI-detectable overall elevated mobile protein level in higher grade tumors. MATERIALS AND METHODS Twelve patients with biopsy-proven prostate cancer were imaged on a 3 Tesla MR imaging system before prostatectomy. APT-MR images were acquired by means of a single-slice single-shot turbo spin… CONTINUE READING

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