American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis

@article{Carceller1992AmericanCO,
  title={American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis},
  author={J. E. Carceller},
  journal={Critical Care Medicine},
  year={1992},
  volume={20},
  pages={864–874}
}
Objective:To define the terms “sepsis” and “organ failure” in a precise manner. Data Sources:Review of the medical literature and the use of expert testimony at a consensus conference. Setting:American College of Chest Physicians (ACCP) headquarters in Northbrook, IL. Participants:Leadership members of ACCP/ Society of Critical Care Medicine (SCCM). Results:An ACCP/SCCM Consensus Conference was held in August of 1991 with the goal of agreeing on a set of definitions that could be applied to… Expand

Paper Mentions

Observational Patient Registry Clinical Trial
Among antibiotic-resistant organisms, the Gram-negative bacteria are now the most important challenge because of the rapid worldwide spread of mechanisms conferring resistance to… Expand
ConditionsCarbapenem Resistant Bacteria Infection
Interventional Clinical Trial
Patients with infections in their blood often become very sick. These patients are usually put in an intensive care unit for careful observation and treatment. These patients may… Expand
ConditionsAgitation, Respiratory Failure, Sepsis
InterventionDrug
Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
TLDR
A consensus process using results from a systematic review, surveys, and cohort studies found that adult patients with septic shock can be identified using the clinical criteria of hypotension requiring vasopressor therapy to maintain mean BP 65 mm Hg or greater and having a serum lactate level greater than 2 mmol/L after adequate fluid resuscitation. Expand
Inclusion criteria for clinical trials in sepsis: did the American College of Chest Physicians/Society of Critical Care Medicine consensus conference definitions of sepsis have an impact?
TLDR
Since 1992 there has been a significant increase in the utilization of predefined sepsis criteria for patient enrollment in clinical trials, and this increase can be attributed to the existence of consensus conference definitions. Expand
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
TLDR
The task force concluded the term severe sepsis was redundant and updated definitions and clinical criteria should replace previous definitions, offer greater consistency for epidemiologic studies and clinical trials, and facilitate earlier recognition and more timely management of patients with sepsi or at risk of developing sepsic shock. Expand
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
TLDR
This document reflects a process whereby a group of experts and opinion leaders revisited the 1992 sepsis guidelines and found that apart from expanding the list of signs and symptoms of sepsi to reflect clinical bedside experience, no evidence exists to support a change to the definitions. Expand
Obesity: Is It a Major Risk for Developing Aspirin Resistance in Older Adults?
TLDR
1. Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Expand
Comparison of International Pediatric Sepsis Consensus Conference Versus Sepsis-3 Definitions for Children Presenting With Septic Shock to a Tertiary Care Center in India: A Retrospective Study*
TLDR
Less than half of children with septic shock identified by International Pediatric Sepsis Consensus Conference definitions were observed to fulfill the criteria for shock as per “Sepsis-3” definitions, which raises questions on the appropriateness of using this definition for diagnosis of septicshock in children. Expand
New definition of sepsis and septic shock: What does it give us?
TLDR
The authors, in the paper on new sepsis definitions, affirmed that SIRS does not represent a dysregu- the authors supported this decision mainly based on a retrospective study conducted in Australia and New Zealand. Expand
Systemic inflammatory response syndrome criteria in defining severe sepsis.
TLDR
The need for two or more SIRS criteria to define severe sepsis excluded one in eight otherwise similar patients with infection, organ failure, and substantial mortality and failed to define a transition point in the risk of death. Expand
Epidemiology of sepsis and septic shock in intensive care units between sepsis-2 and sepsis-3 populations: sepsis prognostication in intensive care unit and emergency room (SPICE-ICU)
TLDR
Most patients with infection admitted to ICU meet sepsis-2 and sepsi-3 criteria, however, in-hospital mortality did not occur if patients did not meet any criteria. Expand
Development and implementation of a multidisciplinary sepsis protocol.
TLDR
A subset of critically ill patients have features characteristic of sepsis despite blood cultures that are repeatedly negative for microorganisms and no identified source of bacterial, fungal, or viral infection. Expand
...
1
2
3
4
5
...