Amelogenin sex determination by pyrosequencing of short PCR products

@article{Tschentscher2008AmelogeninSD,
  title={Amelogenin sex determination by pyrosequencing of short PCR products},
  author={Frank Tschentscher and Ulrich Hermann Frey and Thomas Bajanowski},
  journal={International Journal of Legal Medicine},
  year={2008},
  volume={122},
  pages={333-335}
}
We developed an assay, which allows the sex determination of human DNA samples by pyrosequencing of short PCR products. A 48/45-bp stretch including primers of the amelogenin gene with a 3-bp insertion on the Y chromosome was chosen for analysis. In an initial study, we correctly typed 50 male and 50 female DNA samples from unrelated donors. First experiments with forensic samples, which failed in conventional analyses, indicate that this approach might be an advantage when dealing with… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
10 Citations
14 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 14 references

Similar Papers

Loading similar papers…