Amelogenin proteins of developing dental enamel.

  title={Amelogenin proteins of developing dental enamel.},
  author={Alan G. Fincham and James P. Simmer},
  journal={Ciba Foundation symposium},
  pages={118-30; discussion 130-4}
The amelogenins of developing dental enamel are tissue-specific proteins, rich in proline, leucine, histidine and glutamyl residues, and synthesized by the ameloblast cells of the inner enamel epithelium. These proteins comprise the bulk of the extracellular matrix that becomes mineralized with a hydroxyapatite phase to become the mature enamel. Examination of the amino acid sequences of amelogenins from a range of mammals shows a high degree of evolutionary sequence conservation, suggestive of… CONTINUE READING


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