Ameloblastin Upregulates Inflammatory Response Through Induction of IL-1β in Human Macrophages.

@article{Otsuka2017AmeloblastinUI,
  title={Ameloblastin Upregulates Inflammatory Response Through Induction of IL-1β in Human Macrophages.},
  author={Mai Otsuka and Toshinori Okinaga and Wataru Ariyoshi and Chiaki Kitamura and Tatsuji Nishihara},
  journal={Journal of cellular biochemistry},
  year={2017},
  volume={118 10},
  pages={3308-3317}
}
Ameloblastin (AMBN) is an enamel matrix protein that has various biological functions such as healing dental pulp and repairing bone fractures. In the present study, we clarified the effect of AMBN on the expression of an inflammatory cytokine, interleukin-1β (IL-1β) in lipopolysaccharide (LPS)-treated human macrophages. Real-time RT-PCR analysis showed… CONTINUE READING