Ameloblast differentiation in the human developing tooth: effects of extracellular matrices.

@article{He2010AmeloblastDI,
  title={Ameloblast differentiation in the human developing tooth: effects of extracellular matrices.},
  author={Pingping He and Yan Zhang and Seong Oh Kim and Ralf Johannes Radlanski and Kristin E Butcher and Richard A Schneider and Pamela K Denbesten},
  journal={Matrix biology : journal of the International Society for Matrix Biology},
  year={2010},
  volume={29 5},
  pages={411-9}
}
Tooth enamel is formed by epithelially-derived cells called ameloblasts, while the pulp dentin complex is formed by the dental mesenchyme. These tissues differentiate with reciprocal signaling interactions to form a mature tooth. In this study we have characterized ameloblast differentiation in human developing incisors, and have further investigated the role of extracellular matrix proteins on ameloblast differentiation. Histological and immunohistochemical analyses showed that in the human… CONTINUE READING