Ameliorative effects of vitamin C on short-term sensorimotor and cognitive changes induced by acute chlorpyrifos exposure in Wistar rats.

@article{Ambali2010AmeliorativeEO,
  title={Ameliorative effects of vitamin C on short-term sensorimotor and cognitive changes induced by acute chlorpyrifos exposure in Wistar rats.},
  author={Suleiman Folorunsho Ambali and Sherifat B Idris and Charles Onukak and Mufta'u Shittu and Joseph Olusegun Ayo},
  journal={Toxicology and industrial health},
  year={2010},
  volume={26 9},
  pages={547-58}
}
Human and experimental animal studies have shown long- and short-term neurological sequelae following acute organophosphate (OP) exposure. Although the main molecular mechanism of OP neurotoxiicty involves acetylcholinesterase (AChE) inhibition, studies have also implicated the induction of oxidative stress. The present study was therefore aimed at evaluating the effect of acute chlorpyrifos (CPF) exposure on short-term sensorimotor and cognitive changes in Wistar rats, the role of brain… CONTINUE READING
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