Ameliorative effects of oleanolic acid on fluoride induced metabolic and oxidative dysfunctions in rat brain: Experimental and biochemical studies.

@article{Sarkar2014AmeliorativeEO,
  title={Ameliorative effects of oleanolic acid on fluoride induced metabolic and oxidative dysfunctions in rat brain: Experimental and biochemical studies.},
  author={C. Sarkar and Sudipta Pal and Niranjan Das and B. Dinda},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2014},
  volume={66},
  pages={
          224-36
        }
}
  • C. Sarkar, Sudipta Pal, +1 author B. Dinda
  • Published 2014
  • Chemistry, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • Beneficial effects of oleanolic acid on fluoride-induced oxidative stress and certain metabolic dysfunctions were studied in four regions of rat brain. Male Wistar rats were treated with sodium fluoride at a dose of 20 mg/kg b.w./day (orally) for 30 days. Results indicate marked reduction in acidic, basic and neutral protein contents due to fluoride toxicity in cerebrum, cerebellum, pons and medulla. DNA, RNA contents significantly decreased in those regions after fluoride exposure. Activities… CONTINUE READING
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    References

    SHOWING 1-10 OF 112 REFERENCES
    Protective Role of Gallic Acid on Sodium Fluoride Induced Oxidative Stress in Rat Brain
    • 56
    Effect of silymarin on sodium fluoride-induced toxicity and oxidative stress in rat cardiac tissues.
    • 17
    • PDF
    Protective effects of selenium on fluoride induced alterations in certain enzymes in brain of mice.
    • 39
    • PDF
    Fluoride-Induced Oxidative Stress in Rat’s Brain and Its Amelioration by Buffalo (Bubalus bubalis) Pineal Proteins and Melatonin
    • 62
    [Influence of free radical inducer on the level of oxidative stress in brain of rats with fluorosis].
    • Q. Shao, Y. Wang, Z. Guan
    • Chemistry, Medicine
    • Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]
    • 2000
    • 19
    • PDF
    Effect of fluoride intoxication on lipidperoxidation and antioxidant status in experimental rats.
    • 209
    Efficacy of lycopene against fluoride toxicity in rats
    • 25