Ameliorative effect of selenium in cisplatin-induced testicular damage in rats.

@article{imek2016AmeliorativeEO,
  title={Ameliorative effect of selenium in cisplatin-induced testicular damage in rats.},
  author={Nejdet Şimşek and Akif Koç and Ali Karadeniz and Mehmet Erol Yildirim and H{\"u}seyin Tuğrul Çelik and E Karadag Sari and Adem Kara},
  journal={Acta histochemica},
  year={2016},
  volume={118 3},
  pages={263-70}
}
In this study, we investigated the protective effect of selenium (Se) on cisplatin (Cis) induced testicular damage using histopathological, immunohistochemical and biochemical approaches. Twenty-one male Wistar rats were equally divided into three groups of seven rats each: control (C), Cis, and Cis+Se. Cis and Cis+Se group rats received Cis at a dose of 12mg/kg b.w./day, intraperitoneally for 3 consecutive days. Cis+Se group rats received selenium via oral gavage 3mg/kg/day (twice-a day as 1… CONTINUE READING