Corpus ID: 55282279

Ameliorative Effect of Rutin on Gentamicin-Induced Nephrotoxicity in Murine Model

  title={Ameliorative Effect of Rutin on Gentamicin-Induced Nephrotoxicity in Murine Model},
  author={Ruchi Ramhariya and A. Ganeshpurkar and Chitrangada Ayachi and Piyush Kanojia and Nazneen Dubey and S. Ram and Ganeshpurkar Aditya},
Gentamicin is one of the widely used antibiotics. However, it suffers from drawback of nephrotoxicity, which is predisposed due to oxidative stress. Rutin is one of the major classes of flavonoids and phyto-antioxidant. It has demonstrated cardioprotective, hepatoprotective and neuroprotective effects. However, no studies pertaining to its nephroprotective activity have still performed. Present work was aimed to determine nephroprotective activity of Rutin. Dose of 100 mg/ kg and 200 mg/ kg was… Expand
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