Amelioration of pulmonary pathophysiology of adult respiratory distress syndrome by sulindac, a cyclo-oxygenase inhibitor.

@article{Steinberg1987AmeliorationOP,
  title={Amelioration of pulmonary pathophysiology of adult respiratory distress syndrome by sulindac, a cyclo-oxygenase inhibitor.},
  author={Steven M. Steinberg and Deborah J Dehring and David T. Martin and William Gower and Larry C. Carey and Conrad Cloutier},
  journal={The Journal of trauma},
  year={1987},
  volume={27 12},
  pages={1323-31}
}
The effects of sulindac, a cyclo-oxygenase inhibitor, were tested in a bacteremic porcine model of acute respiratory failure produced by a continuous infusion of live Pseudomonas aeruginosa. Control groups received either a single intravenous dose of sulindac (6 mg/kg) 20 minutes after baseline determinations or a continuous infusion of Ps. aeruginosa (10(7… CONTINUE READING