Amelioration of dementia induced by Aβ 22-35 through rectal delivery of undecapeptide-hEGF to mouse brain.

Abstract

A group of growth factors have been shown to play important roles in amelioration of the malfunction of the neurodegenerative diseases. However, the proteins or polypeptides passing across the blood-brain barrier (BBB) to access the brain parenchyma are relatively few so that it hinders the therapies in clinic. Here a genetically reconstructed fusion… (More)
DOI: 10.1016/j.ijpharm.2010.11.018

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Cite this paper

@article{Zhao2011AmeliorationOD, title={Amelioration of dementia induced by Aβ 22-35 through rectal delivery of undecapeptide-hEGF to mouse brain.}, author={Bao-Quan Zhao and Yan-Ru Guo and Xu-Ling Li and Ting Zang and Heng-Yan Qu and Jian-ping Zhou and Qian Li and Man-ji Sun}, journal={International journal of pharmaceutics}, year={2011}, volume={405 1-2}, pages={1-8} }