Amelioration of collagen-induced arthritis by human recombinant soluble FcgammaRIIb.

@article{Magnusson2008AmeliorationOC,
  title={Amelioration of collagen-induced arthritis by human recombinant soluble FcgammaRIIb.},
  author={Sofia E. Magnusson and Maria Andr{\'e}n and Kajsa E Nilsson and Peter Sondermann and Uwe Jacob and Sandra Kleinau},
  journal={Clinical immunology},
  year={2008},
  volume={127 2},
  pages={225-33}
}
Immune complex (IC) binding to Fc gamma receptors (FcgammaRs) is central for inflammatory reactions seen in autoimmune diseases. Consequently, a therapeutic agent with a possibility to interfere with binding of pathogenic IC to FcgammaRs would be valuable in autoimmune disorders such as rheumatoid arthritis (RA). Here we have explored the therapeutic effect of a recombinant soluble human FcgammaRIIb (sFcgammaRIIb) protein in collagen-induced arthritis (CIA). In vitro studies of the sFcgammaRIIb… CONTINUE READING

Connections & Topics

Mentioned Connections BETA
Consequently , a therapeutic agent with a possibility to interfere with binding of pathogenic IC to FcgammaRs would be valuable in autoimmune disorders such as rheumatoid arthritis ( RA ) .
Consequently , a therapeutic agent with a possibility to interfere with binding of pathogenic IC to FcgammaRs would be valuable in autoimmune disorders such as rheumatoid arthritis ( RA ) .
Consequently , a therapeutic agent with a possibility to interfere with binding of pathogenic IC to FcgammaRs would be valuable in autoimmune disorders such as rheumatoid arthritis ( RA ) .
Consequently , a therapeutic agent with a possibility to interfere with binding of pathogenic IC to FcgammaRs would be valuable in autoimmune disorders such as rheumatoid arthritis ( RA ) .
Consequently , a therapeutic agent with a possibility to interfere with binding of pathogenic IC to FcgammaRs would be valuable in autoimmune disorders such as rheumatoid arthritis ( RA ) .
Consequently , a therapeutic agent with a possibility to interfere with binding of pathogenic IC to FcgammaRs would be valuable in autoimmune disorders such as rheumatoid arthritis ( RA ) .
Consequently , a therapeutic agent with a possibility to interfere with binding of pathogenic IC to FcgammaRs would be valuable in autoimmune disorders such as rheumatoid arthritis ( RA ) .
All Topics