Amelioration of brain pathology and behavioral dysfunction in mice with lupus following treatment with a tolerogenic peptide.

@article{Lapter2009AmeliorationOB,
  title={Amelioration of brain pathology and behavioral dysfunction in mice with lupus following treatment with a tolerogenic peptide.},
  author={Smadar Lapter and Anat Marom and Asher Meshorer and Anat Elmann and Amir Sharabi and Ezra Vadai and Adi Neufeld and Yejezkel Sztainberg and Shoshana Gil and Dmitriy Getselter and Alon Chen and Edna Mozes},
  journal={Arthritis and rheumatism},
  year={2009},
  volume={60 12},
  pages={3744-54}
}
OBJECTIVE Central nervous system (CNS) involvement in systemic lupus erythematosus (SLE) is manifested by neurologic deficits and psychiatric disorders. The aim of this study was to examine SLE-associated CNS pathology in lupus-prone (NZBxNZW)F1 (NZB/NZW) mice, and to evaluate the ameliorating effects of treatment with a tolerogenic peptide, hCDR1 (human… CONTINUE READING