Amelioration of STZ-induced type 1 diabetic nephropathy by aqueous extract of Enicostemma littorale Blume and swertiamarin in rats

@article{Sonawane2010AmeliorationOS,
  title={Amelioration of STZ-induced type 1 diabetic nephropathy by aqueous extract of Enicostemma littorale Blume and swertiamarin in rats},
  author={Rakesh Deelip Sonawane and Santosh L. Vishwakarma and S. Seetha Lakshmi and Mandapati Rajani and Harish Padh and Ramesh K. Goyal},
  journal={Molecular and Cellular Biochemistry},
  year={2010},
  volume={340},
  pages={1-6}
}
Diabetic nephropathy (DN) is one of the foremost causes of renal failure and a primary cause of diabetes mellitus related death. Previously, we have reported that aqueous extract of Enicostemma littorale has potential antidiabetic activity. In the present study, we have investigated the effect of aqueous extract of E. littorale 1 g/kg, p.o. and swertiamarin 50 mg/kg, p.o. daily for 3 weeks in type 1 DN complications in SD rats. DN was assessed by serum urea, creatinine, lipid profile and water… CONTINUE READING

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