Amelioration of Bacterial Genomes: Rates of Change and Exchange

  title={Amelioration of Bacterial Genomes: Rates of Change and Exchange},
  author={Jeffrey G. Lawrence and Howard Ochman},
  journal={Journal of Molecular Evolution},
Although bacterial species display wide variation in their overall GC contents, the genes within a particular species' genome are relatively similar in base composition. As a result, sequences that are novel to a bacterial genome—i.e., DNA introduced through recent horizontal transfer—often bear unusual sequence characteristics and can be distinguished from ancestral DNA. At the time of introgression, horizontally transferred genes reflect the base composition of the donor genome; but, over… CONTINUE READING
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