Amburoside A, a glucoside from Amburanacearensis, protects mesencephalic cells against 6-hydroxydopamine-induced neurotoxicity.

@article{Leal2005AmburosideAA,
  title={Amburoside A, a glucoside from Amburanacearensis, protects mesencephalic cells against 6-hydroxydopamine-induced neurotoxicity.},
  author={Luzia Kalyne Almeida Moreira Leal and H{\'e}lio Vitoriano Nobre J{\'u}nior and Geanne Matos de Andrade Cunha and Manoel Odorico de Moraes and Cl{\'a}udia Pessoa and Ricardo A. O. Oliveira and Edilberto Rocha da Silveira and Kirley Marques Canuto and Glauce Socorro de Barros Viana},
  journal={Neuroscience letters},
  year={2005},
  volume={388 2},
  pages={86-90}
}
This study evaluates the potential neuroprotective properties of amburoside A, a glucoside isolated from Amburana cearensis, on rat mesencephalic cell cultures exposure to the neurotoxin 6-hydroxydopamine (6-OHDA). The parameters determined were cell viability by the 3[4,5-dimethylthiazole-2-il]-2,5-diphenyltetrazolium bromide (MTT) method, nitric oxide (NO) and free radical formation by the measurement of nitrite concentration and thiobarbituric acid reacting substance (TBARS) formation as an… CONTINUE READING
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