Ambiguous genitalia due to partial activity of cytochromes P450c17 and P450c21.

@article{Augarten1992AmbiguousGD,
  title={Ambiguous genitalia due to partial activity of cytochromes P450c17 and P450c21.},
  author={Arie Augarten and Clara Pariente and E. Gazit and R. Chayen and Harold J Goldfarb and Joseph Sack},
  journal={The Journal of steroid biochemistry and molecular biology},
  year={1992},
  volume={41 1},
  pages={37-41}
}
We describe a patient with male pseudohermaphrodism who has normal basal serum concentrations of cortisol and high basal levels of progesterone and 17 hydroxyprogesterone. Serum concentrations of androstendione, dehydroepiandrosterone sulfate and testosterone were low. On adequate human chorionic gonadotropin (HCG) stimulation, no rise in serum androstendione, dehydroepiandrosterone sulfate or testosterone concentrations was observed. After ACTH stimulation there was an excessive rise in… CONTINUE READING