Ambient PM2.5 exposure exacerbates severity of allergic asthma in previously sensitized mice.

OBJECTIVE Epidemiological studies have shown that elevated concentrations of ambient particulate matter (aerodynamic diameter ≤2.5 μm; PM2.5) correlates with increased incidence of asthma. The aim of this study was to determine whether PM2.5 participates in the exacerbation of asthma. METHODS Effects of 1, 10 and 100 μg PM2.5 instilled intratracheally in… CONTINUE READING