Amantadine versus methylphenidate in children and adolescents with attention deficit/hyperactivity disorder: a randomized, double‐blind trial

@article{Mohammadi2010AmantadineVM,
  title={Amantadine versus methylphenidate in children and adolescents with attention deficit/hyperactivity disorder: a randomized, double‐blind trial},
  author={Mohammad Reza Mohammadi and Mohammad Reza Kazemi and Ebtehal Zia and Shamsali Rezazadeh and Mina Tabrizi and Shahin Akhondzadeh},
  journal={Human Psychopharmacology: Clinical and Experimental},
  year={2010},
  volume={25}
}
Objective The aim of the present study was to further evaluate, under double blind and controlled conditions, the efficacy of amantadine for attention‐deficit/hyperactivity disorder (ADHD) in children and adolescents as compared to methylphenidate. 
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23 Citations

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To compare the safety and efficacy of bupropion with methylphenidate in children and adolescents with attention‐deficit/hyperactivity disorder (ADHD).
Memantine versus Methylphenidate in Children and Adolescents with Attention Deficit Hyperactivity Disorder: A Double-Blind, Randomized Clinical Trial
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It was revealed that although memantine was less effective than methylphenidate in the treatment of attention deficit hyperactivity disorder, it may be considered as an alternative treatment.
Buspirone versus methylphenidate in the treatment of children with attention- deficit/ hyperactivity disorder: randomized double-blind study.
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Assessment of the efficacy of buspirone in the treatment of children with ADHD compared to methylphenidate in a double blind, randomized clinical trial suggests that administration of busPirone was less effective than methyl phenidate in the Treatment of ADHD.
Agomelatine as a Treatment for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents: A Double-Blind, Randomized Clinical Trial.
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A treatment course of 6 weeks with agomelatine demonstrated a favorable safety and efficacy profile in children and adolescents with ADHD, and larger controlled studies with longer treatment periods are necessary.
Bupropion in adults with Attention-Deficit/Hyperactivity Disorder: a randomized, double-blind study.
TLDR
Bupropion can be an alternative medication for the treatment of Adults with ADHD as its clinical efficacy was proven by other studies and its theoretical and experimental evidence exists to support efficacy of this medication.
Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of adverse events in non-randomised studies.
TLDR
A systematic review of randomised clinical trials (RCTs) for methylphenidate treatment for children and adolescents with ADHD demonstrated no increase in serious adverse events, but a high proportion of participants suffered a range of non-serious adverse events.
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TLDR
Network meta-analysis offered a broader overview on the available treatments for ADHD, especially for safety issues, and contributes towards evidence gathering and clinical practice decisions.
Advances and considerations in attention-deficit/hyperactivity disorder pharmacotherapy.
TLDR
This review focuses on etiology, assessment and treatment of ADHD with various stimulant and non-stimulant agents.
Amantadine: a review of use in child and adolescent psychiatry.
  • Sheik HosenbocusRaj Chahal
  • Psychology, Medicine
    Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent
  • 2013
TLDR
Amantadine shows potential for use as a safe alternative or as an augmenting agent for treating children with neuropsychiatric and various other disorders and available data for such use, although promising, require further confirmation.
Emerging drugs for the treatment of attention-deficit hyperactivity disorder (ADHD)
TLDR
A review of the scientific literature and of unpublished/ongoing clinical trials to summarize the advances made in the last 10 years for the pharmacological treatment of ADHD found many pharmacological mechanisms beyond dopaminergic and noradrenergic ones have been investigated in patients.
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