Amantadine as augmentation therapy in the management of treatment-resistant depression.

@article{Stryjer2003AmantadineAA,
  title={Amantadine as augmentation therapy in the management of treatment-resistant depression.},
  author={Rafael Stryjer and Rael David Strous and Ginette Shaked and Faina Bar and Boris Feldman and Moshe Kotler and Lea Polak and Silvio Rosenzcwaig and Abraham Weizman},
  journal={International clinical psychopharmacology},
  year={2003},
  volume={18 2},
  pages={93-6}
}
Treatment-resistant depression is an important clinical problem presenting a major challenge to clinical psychiatry. While several strategies have been attempted, including medication switch, antidepressant polypharmacy and various augmentative regimens, success remains limited. Amantadine (AMN), an agent traditionally used in the treatment and prophylaxis… CONTINUE READING