Amantadine: the journey from fighting flu to treating Parkinson disease.

Abstract

OBJECTIVE To explore how amantadine transitioned from an anti-flu drug to antiparkinsonian agent. METHODS A review of the historical literature on the use of amantadine from 1966 to the present was performed. RESULTS Amantadine was originally introduced and utilized as an antiviral medication. A single patient noticed relief in her Parkinson disease (PD… (More)
DOI: 10.1212/WNL.0b013e31824e8f0d

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