Amanita Muscaria (Fly Agaric): From a Shamanistic Hallucinogen to the Search for Acetylcholine

  title={Amanita Muscaria (Fly Agaric): From a Shamanistic Hallucinogen to the Search for Acetylcholine},
  author={MR Lee and Estela Dukan and Iain A. Milne},
  journal={Journal of the Royal College of Physicians of Edinburgh},
  pages={85 - 91}
  • M. Lee, E. Dukan, I. Milne
  • Published 1 March 2018
  • Biology
  • Journal of the Royal College of Physicians of Edinburgh
The mushroom Amanita muscaria (fly agaric) is widely distributed throughout continental Europe and the UK. Its common name suggests that it had been used to kill flies, until superseded by arsenic. The bioactive compounds occurring in the mushroom remained a mystery for long periods of time, but eventually four hallucinogens were isolated from the fungus: muscarine, muscimol, muscazone and ibotenic acid. The shamans of Eastern Siberia used the mushroom as an inebriant and a hallucinogen. In… 
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