Amadori‐glycated phosphatidylethanolamine induces angiogenic differentiations in cultured human umbilical vein endothelial cells

@article{Oak2003AmadoriglycatedPI,
  title={Amadori‐glycated phosphatidylethanolamine induces angiogenic differentiations in cultured human umbilical vein endothelial cells},
  author={Jeong‐Ho Oak and Kiyotaka Nakagawa and Shin'ichi Oikawa and Teruo Miyazawa},
  journal={FEBS Letters},
  year={2003},
  volume={555}
}
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References

SHOWING 1-10 OF 29 REFERENCES
Advanced Glycation End Products-driven Angiogenesis in Vitro
TLDR
The results suggest that AGE can elicit angiogenesis through the induction of autocrine vascular VEGF, thereby playing an active part in the development and progression of diabetic microangiopathies.
Angiogenic effects of advanced glycation end products of the Maillard reaction on cultured human umbilical cord vein endothelial cells.
TLDR
The effects of advanced glycation end products of the Maillard reaction on proliferation, migration and angiogenesis of cultured human umbilical vein endothelial cells were studied and provide evidence that AGE are angiogenic.
Synthetically prepared Amadori‐glycated phosphatidylethanolamine can trigger lipid peroxidation via free radical reactions
Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention.
TLDR
Understanding the cellular events involved in angiogenesis and the molecular regulation of these events has enormous clinical implications and is providing novel therapeutic targets for the treatment of a variety of diseases, including cancer.
Reactive oxygen species accelerate production of vascular endothelial growth factor by advanced glycation end products in RAW264.7 mouse macrophages.
Advanced glycation end products induce angiogenesis in vivo.
TLDR
The data demonstrated that AGEs are an angiogenetic factor and that the system of AGE-induced abnormal vessels in CAMs is useful in further investigations of the mechanism of diabetic retinal angiogenesis and can also be used to provide a therapeutic model for diabetic angiopathy.
Regulation of matrix metalloproteinase expression in human vein and microvascular endothelial cells. Effects of tumour necrosis factor alpha, interleukin 1 and phorbol ester.
TLDR
The inflammatory mediator TNF alpha induces/enhances the production of several matrix metalloproteinases in human endothelial cells, while MMP-2 and TIMP-2 were not affected or were affected in a variable way by TNFalpha and/or phorbol ester, suggesting a dissimilar regulation of these proteins.
Vascular pericytes not only regulate growth, but also preserve prostacyclin-producing ability and protect against lipid peroxide-induced injury of co-cultured endothelial cells.
TLDR
Results indicate that pericytes provide instructive signals to adjacent endothelial cells, helping to maintain microvascular homeostasis.
UV analysis of Amadori-glycated phosphatidylethanolamine in foods and biological samples.
TLDR
This study synthesized the Amadori products derived from the glycation of phosphatidylethanolamine (PE) using solid phase extraction followed by HPLC, and testing biological materials showedAmadori-PE (Glc-PE) was detectable in rat plasma.
Glucosylated glycerophosphoethanolamines are the major LDL glycation products and increase LDL susceptibility to oxidation: evidence of their presence in atherosclerotic lesions.
TLDR
Inclusion of glucosylated phosphatidylethanolamine in the surface lipid monolayer of the LDL resulted in rapid loss of polyunsaturated cholesteryl esters from the interior of the particle during oxidation.
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