Amadori‐glycated phosphatidylethanolamine up‐regulates telomerase activity in PANC‐1 human pancreatic carcinoma cells

  title={Amadori‐glycated phosphatidylethanolamine up‐regulates telomerase activity in PANC‐1 human pancreatic carcinoma cells},
  author={T. Eitsuka and K. Nakagawa and Y. Ono and Naoto Tatewaki and H. Nishida and T. Kurata and Naoki Shoji and T. Miyazawa},
  journal={FEBS Letters},
Several lines of experimental data have highlighted a key role of Amadori‐glycated phosphatidylethanolamine (Amadori‐PE) in the development of diabetic complications. Recent epidemiological studies suggest that diabetes mellitus could be a risk factor for some cancers. A characteristic of cancer cells is their immortal phenotype, and the enzyme telomerase contributes to the infinite replicative potential of cancer cells. The purpose of this study was to obtain new information about the effect… Expand
6 Citations
Modulation of Telomerase Activity in Cancer Cells by Dietary Compounds: A Review
  • 15
  • PDF
Immunonutritional Bridge to Liver Health
The bidirectional interation between pancreatic cancer and diabetes
  • 32
Lipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipids.
  • 43


Down-regulation of telomerase activity in DLD-1 human colorectal adenocarcinoma cells by tocotrienol.
  • 83
hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization
  • 1,827
  • PDF
Synthetically prepared Amadori‐glycated phosphatidylethanolamine can trigger lipid peroxidation via free radical reactions
  • 72
Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer.
  • 313
  • PDF
Do conjugated eicosapentaenoic acid and conjugated docosahexaenoic acid induce apoptosis via lipid peroxidation in cultured human tumor cells?
  • 64
Low molecular weight inhibitors of Myc–Max interaction and function
  • 342
  • PDF