Alzheimer's disease: charting the crossroads between neurology and psychology.


Neurodegenerative disorders such as Alzheimer's disease (AD) are increasingly recognised to have a long prodromal stage before the onset of symptoms defining the dementia syndrome. This phase may last up to years or even decades. An intensive search has been initiated for signs or symptoms that might enable prediction of dementia development.1 The motivation for identifying such predictors comes from the assumption that disease-modifying treatment might be more effective in early or even presymptomatic stages when the pathogenic mechanisms have not progressed, and irreversible damage to neurons and neural networks is still limited. Therefore, early recognition of imminent dementia may play an important role in the future.

DOI: 10.1136/jnnp-2012-304479

Cite this paper

@article{Gilbert2014AlzheimersDC, title={Alzheimer's disease: charting the crossroads between neurology and psychology.}, author={Thomas E. Gilbert and Martin Herbst}, journal={Journal of neurology, neurosurgery, and psychiatry}, year={2014}, volume={85 2}, pages={133-4} }