Alzheimer disease, attention, and the cholinergic system.

  title={Alzheimer disease, attention, and the cholinergic system.},
  author={Andrew D. Lawrence and Barbara J. Sahakian},
  journal={Alzheimer disease and associated disorders},
  volume={9 Suppl 2},
Recent neuropsychological studies suggest that, in addition to prominent mnemonic dysfunction, attentional impairments are a core feature of Alzheimer disease (AD). As is the case for memory, attention is not a unitary process, and only certain components of attention are disrupted in mild AD, particularly sustained and spatial attention. In this article we review evidence from both human and nonhuman neuropsychopharmacology that leads us to suggest that (at least some of) the attentional… CONTINUE READING


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