Alzheimer's disease and sleep disturbances: a review.

  title={Alzheimer's disease and sleep disturbances: a review.},
  author={Conrado Regis Borges and Dalva R Poyares and Ronaldo Delmonte Piovezan and Ricardo Nitrini and Sonia Maria Dozzi Brucki},
  journal={Arquivos de neuro-psiquiatria},
  volume={77 11},
The association between Alzheimer's disease (AD) and sleep disturbances has received increasing scientific attention in the last decades. However, little is known about the impact of sleep and its disturbances on the development of preclinical AD stages, such as mild cognitive impairment. This review describes the evolution of knowledge about the potential bidirectional relationships between AD and sleep disturbances exploring recent large prospective studies and meta-analyses and studies of… 

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