• Corpus ID: 212511375

Alzheimer’s Disease: A Novel Hypothesis Integrating Spirochetes, Biofilm, and the Immune System

  title={Alzheimer’s Disease: A Novel Hypothesis Integrating Spirochetes, Biofilm, and the Immune System},
  author={Herbert B. Allen and Diego Morales and Krister Jones and Suresh G. Joshi},
In the light of recent studies showing the presence of spirochetes in the brains of Alzheimer’s disease (AD) patients, we have studied (post mortem) the hippocampus region in the brains of similarly affected AD patients utilizing both pathology and immunohistochemistry. Our findings demonstrate that the plaques, which are characteristically found in AD brains, reveal the presence of biofilms. These biofilms are undoubtedly made by the spirochetes present there; further, we have also found that… 

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