Alzheimer's disease comorbidity in normal pressure hydrocephalus: prevalence and shunt response.

@article{Golomb2000AlzheimersDC,
  title={Alzheimer's disease comorbidity in normal pressure hydrocephalus: prevalence and shunt response.},
  author={J Golomb and Jessica Wisoff and Douglas Craig Miller and Istvan Boksay and Angelika Kluger and Henry Weiner and Justine A. Salton and W. Graves},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2000},
  volume={68 6},
  pages={778-81}
}
The clinical impact of Alzheimer's disease pathology at biopsy was investigated in 56 cognitively impaired patients undergoing shunt surgery for idiopathic normal pressure hydrocephalus (NPH). Cognition was measured by means of the global deterioration scale (GDS), the mini mental status examination (MMSE) and a battery of six psychometric tests. Gait was assessed using objective measurements of velocity and the ambulatory index (AI). The prevalence of cases exhibiting neuritic plaques… CONTINUE READING