Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches

@article{Behl1999AlzheimersDA,
  title={Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches},
  author={Christian Behl},
  journal={Progress in Neurobiology},
  year={1999},
  volume={57},
  pages={301-323}
}
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a deadly outcome. AD is the leading cause of senile dementia and although the pathogenesis of this disorder is not known, various hypotheses have been developed based on experimental data accumulated since the initial description of this disease by Alois Alzheimer about 90 years ago. Most approaches to explain the pathogenesis of AD focus on its two histopathological hallmarks, the amyloid beta protein- (A(beta)-) loaded… CONTINUE READING

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