Alzheimer's disease: pathophysiological implications of measurement of plasma cortisol, plasma dehydroepiandrosterone sulfate, and lymphocytic corticosteroid receptors.

@article{Armanini2003AlzheimersDP,
  title={Alzheimer's disease: pathophysiological implications of measurement of plasma cortisol, plasma dehydroepiandrosterone sulfate, and lymphocytic corticosteroid receptors.},
  author={Decio Armanini and Franco Vecchio and Alfonso Basso and Francesco Ferro Milone and Maria Simoncini and Cristina Fiore and Mee Joung Mattarello and Paola Sartorato and Isabella Karbowiak},
  journal={Endocrine},
  year={2003},
  volume={22 2},
  pages={113-8}
}
Alzheimer's disease is often characterized by an increase in plasma cortisol without clinical evidence of hypercorticism. Twenty-three consecutive patients with Alzheimer's disease and 23 age- and sex-matched healthy controls were studied by measuring plasma cortisol and dehydroepiandrosterone sulfate (DHEAS) (by enzyme immunoassay), the number of type I and type II corticosteroid receptors in mononuclear leukocytes (by radio-receptor-assay), and the lymphocyte subpopulations (by… CONTINUE READING