Alzheimer's disease: The role for neurosurgery

  title={Alzheimer's disease: The role for neurosurgery},
  author={J{\'u}lio Leonardo Barbosa Pereira and Angela Downes and Alessandra Gorgulho and Vishal Patel and Dennis R Malkasian and Antonio A. F. De Salles},
  booktitle={Surgical neurology international},
Dementia, most commonly caused by Alzheimer's disease (AD), affects approximately 35 million people worldwide, with the incidence expected to increase as the population ages. After decades of investigation, AD is now understood to be a complex disease that affects behavior and cognition through several mechanisms: Disrupted neuronal communication, abnormal regional tissue metabolism, and impaired cellular repair. Existing therapies have demonstrated limited efficacy, which has spurred the… CONTINUE READING
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