Alzheimer's disease, Parkinson's disease, and motoneurone disease: abiotrophic interaction between ageing and environment?

@article{Calne1986AlzheimersDP,
  title={Alzheimer's disease, Parkinson's disease, and motoneurone disease: abiotrophic interaction between ageing and environment?},
  author={Donald B. Calne and A. Eisen and E. G. McGeer P. L. McGeer and Pamela Spencer},
  journal={Lancet},
  year={1986},
  volume={2 8515},
  pages={1067-70}
}
The hypothesis is that Alzheimer's disease, Parkinson's disease (PD), and motoneurone disease are due to environmental damage to specific regions of the central nervous system and that the damage remains subclinical for several decades but makes those affected especially prone to the consequences of age-related neuronal attrition. This proposal is based on the association between environmental factors and certain neurodegenerative diseases (eg, methylphenyltetra-hydropyridine and parkinsonism… CONTINUE READING

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