Alzheimer's Disease: Genomics and Beyond.

  title={Alzheimer's Disease: Genomics and Beyond.},
  author={Fuhai Song and Guangchun Han and Zhouxian Bai and Xing Peng and Jiajia Wang and Hongxing Lei},
  journal={International review of neurobiology},
Alzheimer's disease (AD) is a major form of senile dementia. Despite the critical roles of Aβ and tau in AD pathology, drugs targeting Aβ or tau have so far reached limited success. The advent of genomic technologies has made it possible to gain a more complete picture regarding the molecular network underlying the disease progression which may lead to discoveries of novel treatment targets. In this review, we will discuss recent progresses in AD research focusing on genome, transcriptome… CONTINUE READING