Alvimopan

▲ Alvimopan, a trans-3,4-dimethyl-4-(3-hydroxy-phenyl) piperidine, is a selective, peripherally acting μ-opioid receptor antagonist that is available for short-term use in hospitalized patients who have undergone bowel resection. ▲ The efficacy of alvimopan in the management of postoperative ileus has been evaluated in five phase III trials; four conducted… CONTINUE READING