Alvimopan, a selective peripherally acting mu-opioid antagonist.

  title={Alvimopan, a selective peripherally acting mu-opioid antagonist.},
  author={Michael Camilleri},
  journal={Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society},
  volume={17 2},
  • Michael Camilleri
  • Published 2005 in
    Neurogastroenterology and motility : the official…
Alvimopan is a novel, peripherally acting mu-opioid antagonist that is being developed for the management of acute postoperative ileus and for the reversal of the delayed gastrointestinal and colonic transit that result in symptoms such as constipation, nausea and motility disorders in patients treated with opiate analgesics. There is a clinical need for effective medications for the treatment of postoperative ileus and opiate-induced constipation and other motility disorders. This review… CONTINUE READING


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