Alveolar plasminogen activator inhibitor-1 predicts ARDS in aspiration pneumonitis

  title={Alveolar plasminogen activator inhibitor-1 predicts ARDS in aspiration pneumonitis},
  author={Ali A. El Solh and Milapchand Bhora and Lilibeth A Pineda and Alan T Aquilina and Laurie Abbetessa and Eileen Berbary},
  journal={Intensive Care Medicine},
To test the hypothesis that alveolar plasminogen activator inhibitor-1 (PAI-1) can identify patients with witnessed aspiration at risk for progression to acute respiratory distress syndrome (ARDS). Prospective observational study. Medical intensive care unit in a tertiary care center. Fifty-one patients with witnessed aspiration who had a PaO2/FIO2<300 for a period no less than 4 h from admission. Alveolar fluid sampling was performed within 8 h of intubation via luminal suction of the distal… CONTINUE READING


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Proco - agulant and fibrinolytic activity in ventilator - associated pneumonia : impact of inadequate antimicrobial thera

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