Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment

@article{Ishii2005AlveolarMC,
  title={Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment},
  author={Hiroshi Ishii and Shizu Hayashi and James C. Hogg and Takeshi Fujii and Yukinobu Goto and Noriho Sakamoto and Hiroshi Mukae and Renaud Vincent and Stephan F. van Eeden},
  journal={Respiratory Research},
  year={2005},
  volume={6},
  pages={87 - 87}
}
BACKGROUND Studies from our laboratory have shown that human alveolar macrophages (AM) and bronchial epithelial cells (HBEC) exposed to ambient particles (PM10) in vitro increase their production of inflammatory mediators and that supernatants from PM10-exposed cells shorten the transit time of monocytes through the bone marrow and promote their release into the circulation. METHODS The present study concerns co-culture of AM and HBEC exposed to PM10 (EHC-93) and the production of mediators… CONTINUE READING
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