Alveolar leak develops by a rich-get-richer process in ventilator-induced lung injury

@inproceedings{Hamlington2018AlveolarLD,
  title={Alveolar leak develops by a rich-get-richer process in ventilator-induced lung injury},
  author={K. L. Hamlington and Jason H. T. Bates and Gregory S. Roy and Adele J Julianelle and Chantel M. Charlebois and B{\'e}la Suki and Bradford J. Smith},
  booktitle={PloS one},
  year={2018}
}
Acute respiratory distress syndrome (ARDS) is a life-threatening condition for which there are currently no medical therapies other than supportive care involving the application of mechanical ventilation. However, mechanical ventilation itself can worsen ARDS by damaging the alveolocapillary barrier in the lungs. This allows plasma-derived fluid and proteins to leak into the airspaces of the lung where they interfere with the functioning of pulmonary surfactant, which increases the stresses of… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 43 REFERENCES

Linking alveolar epithelial barrier disruption to function in ventilator - induced lung injury

KL Hamlington, CM Dunn, GS Roy, BJ Smith, Bates JHT
  • Am J Respir Crit Care Med
  • 2016

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