Alveolar bone regeneration by transplantation of periodontal ligament stem cells and bone marrow stem cells in a canine peri-implant defect model: a pilot study.

@article{Kim2009AlveolarBR,
  title={Alveolar bone regeneration by transplantation of periodontal ligament stem cells and bone marrow stem cells in a canine peri-implant defect model: a pilot study.},
  author={Su-Hwan Kim and Kyoung-Hwa Yonnie Kim and B Seo and Ki-Tae Koo and Tae-Il Kim and Yang Jo Seol and Young Jun Ku and In-Chul Rhyu and C Chung and Yong Moo Lee},
  journal={Journal of periodontology},
  year={2009},
  volume={80 11},
  pages={1815-23}
}
BACKGROUND The present study was undertaken to evaluate the potential of periodontal ligament stem cells (PDLSCs) and bone marrow SCs (BMSCs) on alveolar bone regeneration in a canine peri-implant defect model. METHODS Four adult, male beagle dogs were used in this study. Autologous BMSCs from the iliac crests and PDLSCs from extracted teeth were cultured. Three months after extraction, BMSC- and PDLSC-loaded hydroxyapatite/beta-tricalcium phosphate (HA/TCP) (test groups) and cell-free HA/TCP… CONTINUE READING