Aluminum exchange between citrate and human serum transferrin and interaction with transferrin receptor 1.

@article{Hemadi2003AluminumEB,
  title={Aluminum exchange between citrate and human serum transferrin and interaction with transferrin receptor 1.},
  author={M. Hemadi and Genevi{\`e}ve Miquel and Philippe H Kahn and Jean-Michel El Hage Chahine},
  journal={Biochemistry},
  year={2003},
  volume={42 10},
  pages={3120-30}
}
The kinetics and thermodynamics of Al(III) exchange between aluminum citrate (AlL) and human serum transferrin were investigated in the 7.2-8.9 pH range. The C-site of human serum apotransferrin in interaction with bicarbonate removes Al(III) from Al citrate with an exchange equilibrium constant K1 = (2.0 +/- 0.6) x 10(-2); a direct second-order rate… CONTINUE READING