Aluminum bone toxicity in immature rats exposed to simulated high altitude

@article{Martnez2010AluminumBT,
  title={Aluminum bone toxicity in immature rats exposed to simulated high altitude},
  author={Mar{\'i}a Pilar Mart{\'i}nez and C. Bozzini and M. I. Olivera and G. Dmytrenko and M. I. Conti},
  journal={Journal of Bone and Mineral Metabolism},
  year={2010},
  volume={29},
  pages={526-534}
}
Aluminum (Al) is an element to which humans are widely exposed. Chronic administration induces a negative effect on bone tissue, affecting collagen synthesis and matrix mineralization. Its toxic effects are cumulative. Hypobaric hypoxia induces stress erythropoiesis, leading to hypertrophy of the erythropoietic marrow affecting the bone. This study was designed to evaluate the risk of Al bone toxicity among immature rats maintained at simulated high altitude (SHA) by mechanical assessment of… Expand
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