Aluminum-Induced neurotoxicity: Alterations in membrane function at the blood-brain barrier

@article{Banks1989AluminumInducedNA,
  title={Aluminum-Induced neurotoxicity: Alterations in membrane function at the blood-brain barrier},
  author={W. Banks and A. Kastin},
  journal={Neuroscience & Biobehavioral Reviews},
  year={1989},
  volume={13},
  pages={47-53}
}
  • W. Banks, A. Kastin
  • Published 1989
  • Chemistry, Medicine
  • Neuroscience & Biobehavioral Reviews
  • Aluminum is established as a neurotoxin, although the basis for its toxicity is unknown. It recently has been shown to alter the function of the blood-brain barrier (BBB), which regulates exchanges between the central nervous system (CNS) and peripheral circulation. The BBB owes its unique properties to the integrity of the cell membranes that comprise it. Aluminum affects some of the membrane-like functions of the BBB. It increases the rate of transmembrane diffusion and selectively changes… CONTINUE READING
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